Targeting a gene regulatory element enhances
WebOct 29, 2015 · Abstract. Transcription factors (TFs) bind specific sequences in promoter-proximal and -distal DNA elements to regulate gene transcription. RNA is transcribed … WebRice gene IPA1 increases the number of grains per panicle but reduces the number of tillers, two traits offsetting each other for yield. The authors demonstrated that the deletion of a …
Targeting a gene regulatory element enhances
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WebHere we review these results, focusing on the factors that determine the promoter and/or enhancer activity of regulatory elements. We discuss emerging models that define regulatory elements by accessible DNA and their non-mutually-exclusive abilities to drive transcription initiation (promoter activity) and/or to enhance transcription at other ... WebFeb 1, 2024 · Gene regulatory variation. The epigenome is not the only non-genic factor influencing plant traits; gene regulatory variation has long been a prominent consideration …
WebApr 22, 2024 · Targeting a gene regulatory element enhances rice grain yield by decoupling panicle number and size. 2024 Sep;40 (9):1403-1411. doi: 10.1038/s41587-022-01281-7. …
WebAug 30, 2024 · Figure 1. Gene regulatory networks: Gene regulatory networks (GRNs) can be schematized using arrows with pointed and flat ends to show how genes affect each other. A pointed arrow (→) indicates that the protein product of one gene turns another gene on. A flat headed arrow (⊣) indicates that the protein product of one gene turns another gene off. WebMar 11, 2014 · Enhancers are DNA elements that are key regulators of gene expression, but their complexities and context dependence makes their identification and …
We systematically dissected the CRRs of IPA1 by creating and investigating a series of genome-edited lines with deletions in the IPA1 promoter, untranslated regions (UTRs) and downstream region by CRISPR–Cas9 (Fig. 1a). We used the certified variety Zhonghua 11 (ZH11) as the genetic background to fully … See more Among these lines, we found that one line, IPA1-Pro10, which harbored a 54-bp deletion in the IPA1 promoter (this 54-bp was designated as IPA1-Pro10 fragment), … See more We searched for the possible transcription factor binding sites and found a potential binding motif ‘GCGCGTGT’ of An-1 in this region (Fig. 4a and Supplementary … See more Near-isogenic line (NIL) NIL-an-1 is an awnless indica variety NA93-11 carrying a loss-of-function An-1 allele with a frameshift mutation, and NIL-An-1 is an … See more
WebApr 21, 2024 · Mechanistic studies revealed that the deleted fragment is a target site for the transcription factor An-1 to repress IPA1 expression in panicles and roots. Targeting gene … butterfly tattoos on buttocksWeb当前位置: »论坛 › 学术社区 › 学术文献互助交流/求助 › Targeting a gene regulatory element enhances rice gr ... [Nature] Targeting a gene regulatory element enhances rice grain … ce che schedeWebARTICLES NATURE BIOTECHNOLOGY a b c d e 0 5 10 15 01 2 Relative level of IPA1 in shoot base 2 Tiller number 4 6 1 2 3 Panicle weight (g) Relative level of IPA1 in ... butterfly tattoos on arms